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Growth Hormone & Secretagogues · 10mg
Janoshik-tested · 10 vials per kit
GHRP-2 is a synthetic hexapeptide growth hormone secretagogue studied in preclinical research for its GH-releasing properties. Research has examined its potential to stimulate GH release via ghrelin receptor agonism, increase IGF-1 levels, and modulate appetite. Studies have also explored potential anti-inflammatory and cardioprotective effects in animal models.
≥98%
Purity
Lyophilised
Format
2–3 wks
Arrival
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Research Use Only — Disclaimer
This product is intended solely as a research chemical for laboratory and scientific study purposes only. It is not approved by the TGA or any regulatory body for human or animal consumption, therapeutic use, or clinical application. The information provided on this website is for educational purposes only. Handling must be limited to suitably qualified professionals operating within applicable laws and regulations. This product is not classified as a drug, food, cosmetic, or medicinal product and must not be used or labelled as such. By purchasing, you confirm you are a qualified research professional and accept full responsibility for compliance with all relevant laws in your jurisdiction.
GHRP-2
Growth Hormone Releasing Peptide-2
GHRP-2 (Pralmorelin, KP-102) is a synthetic hexapeptide and potent GH secretagogue receptor (GHS-R1a) agonist. Developed in the 1980s from research into enkephalin analogs that release GH, it is among the most potent GHS-R1a agonists per milligram. Approved in Japan as a diagnostic agent (GHRELIN) for GH secretion testing. Its GH-releasing potency exceeds Ipamorelin's but is accompanied by greater cortisol and prolactin stimulation.
GHRP-2 is a GHS-R1a agonist on pituitary somatotrophs (primary GH-releasing action) and on hypothalamic GHRH neurons (secondary amplification via stimulating additional GHRH release). This dual-site activity produces GH pulses larger than hypothalamic-only stimulation. GHRP-2 also stimulates cortisol via ACTH release and prolactin via pituitary lactotrophs. Combined with a GHRH analog (CJC-1295, Sermorelin), the two pathways activate complementary intracellular cascades — cAMP/PKA (GHRH) + IP3/PKC (GHRP) — for synergistic GH amplification.
GH secretagogue protocols, body composition, GH axis pharmacology, appetite stimulation (ghrelin pathway activation), and GH deficiency assessment (its use as a diagnostic GH stimulation test in Japan). Research also explores its role in cardiac protection (independent of GH, GHS-R1a is expressed in cardiac tissue).
For research reference only. All information pertains to preclinical or published human trial data. Not intended as medical advice. This product is for research use only.
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