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Regenerative & Anti-Aging · 600mg
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Janoshik-tested · 10 vials per kit
Glutathione (GSH) is a tripeptide antioxidant naturally produced in the liver, studied in preclinical and clinical research for its cytoprotective and detoxification properties. Research has examined its potential to neutralise reactive oxygen species, support phase II liver detoxification, regenerate vitamins C and E, modulate immune function, and protect cells from oxidative stress-related damage.
≥98%
Purity
Lyophilised
Format
2–3 wks
Arrival
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Research Use Only — Disclaimer
This product is intended solely as a research chemical for laboratory and scientific study purposes only. It is not approved by the TGA or any regulatory body for human or animal consumption, therapeutic use, or clinical application. The information provided on this website is for educational purposes only. Handling must be limited to suitably qualified professionals operating within applicable laws and regulations. This product is not classified as a drug, food, cosmetic, or medicinal product and must not be used or labelled as such. By purchasing, you confirm you are a qualified research professional and accept full responsibility for compliance with all relevant laws in your jurisdiction.
GSH Glutathione
γ-L-Glutamyl-L-Cysteinyl-Glycine
Glutathione (γ-L-glutamyl-L-cysteinyl-glycine, GSH) is the most abundant intracellular antioxidant tripeptide, present at 0.5-10 mM concentrations in virtually all mammalian cells. Synthesised from glutamate, cysteine, and glycine by glutamate-cysteine ligase (GCL) and glutathione synthetase (GS). GSH levels decline with age, oxidative stress, toxic exposures, and chronic disease — making replenishment a focus of both anti-ageing and hepatoprotective research.
GSH serves multiple overlapping roles: as the primary electron donor for glutathione peroxidase (GPx) enzymes — the main intracellular defence against hydrogen peroxide and lipid hydroperoxides; as the redox buffer (GSH/GSSG ratio) that maintains the reducing intracellular environment; as a substrate for glutathione S-transferase (GST) enzymes that conjugate and neutralise electrophilic toxins and reactive metabolites; and as a direct participant in the gamma-glutamyl cycle for amino acid transport. In melanocytes, GSH inhibits tyrosinase, reducing eumelanin synthesis.
Intravenous glutathione has been studied for liver protection (hepatitis, alcoholic liver disease, chemotherapy-induced hepatotoxicity), detoxification support (heavy metal chelation adjunct, xenobiotic clearance), immune function enhancement (GSH is essential for T-cell proliferation and NK cell activity), skin brightening (tyrosinase inhibition), mitochondrial protection, and neurodegenerative disease (Parkinson's disease — intravenous GSH trials showed symptomatic improvement in early studies).
Key References
For research reference only. All information pertains to preclinical or published human trial data. Not intended as medical advice. This product is for research use only.
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