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Hormonal & Fertility Support · 2000iu
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Janoshik-tested · 10 vials per kit
HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone studied in preclinical and clinical research for its reproductive and endocrine properties. Research has examined its potential to stimulate Leydig cells to produce testosterone in males, trigger ovulation in females, support corpus luteum function, and maintain hormonal balance in fertility protocols. Studies have also explored applications in hypogonadism and fertility research models.
≥98%
Purity
Lyophilised
Format
2–3 wks
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Research Use Only — Disclaimer
This product is intended solely as a research chemical for laboratory and scientific study purposes only. It is not approved by the TGA or any regulatory body for human or animal consumption, therapeutic use, or clinical application. The information provided on this website is for educational purposes only. Handling must be limited to suitably qualified professionals operating within applicable laws and regulations. This product is not classified as a drug, food, cosmetic, or medicinal product and must not be used or labelled as such. By purchasing, you confirm you are a qualified research professional and accept full responsibility for compliance with all relevant laws in your jurisdiction.
HCG
Human Chorionic Gonadotropin
Human Chorionic Gonadotropin (hCG) is a heterodimeric glycoprotein hormone composed of shared alpha (92 aa) and unique beta (145 aa) subunits, produced by the placental syncytiotrophoblast during pregnancy. Recombinant hCG (Ovitrelle) and highly-purified urinary hCG preparations are used extensively in reproductive medicine. In the research setting, hCG functions as a long-acting LH surrogate due to its shared receptor and ~24-hour half-life (vs LH's ~30 minutes).
hCG binds the luteinising hormone/choriogonadotropin receptor (LHCGR) with high affinity, activating cAMP/PKA signalling in target cells. In Leydig cells, LHCGR activation upregulates StAR protein (mitochondrial cholesterol transport) and CYP11A1 (cholesterol side-chain cleavage enzyme), driving testosterone biosynthesis. In ovarian granulosa cells, the LH-surge equivalent produced by hCG triggers ovulation and corpus luteum formation and progesterone secretion.
Testosterone production stimulation in hypogonadism research, prevention of testicular atrophy and maintenance of intratesticular testosterone during androgen administration protocols, fertility protocols (ovulation induction, luteal phase support, spermatogenesis stimulation in hypogonadotrophic hypogonadism), and LH-receptor pharmacology. As the longest-acting endogenous-equivalent gonadotropin, hCG is a valuable tool in HPG-axis research.
For research reference only. All information pertains to preclinical or published human trial data. Not intended as medical advice. This product is for research use only.
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